Enhanced identification of significant regulators of gene expression.

GO terms were excluded because the initial set of genes is based on their role in gene regulation (like transcription factors), therefore all GO terms related to gene regulation will be highly significant, which will then dominate the analysis, whereas in this case we want to focus on what we can learn in addition to what we already know.

also in 132,142 other papers

The PubMed analysis is a simplistic approach, and it assumes a relatively standardized use of gene names in publications, but it still shows a clear trend, where the alternative metrics Sobolev and Fisher consistently have retrieved the gene sets with most publications, with the Fisher metric doing slightly better than Sobolev.

also in 19,460 other papers