α 1 -Adrenergic Stimulation of Aortic Segments With 1 μM Phenylephrine In endothelium-intact segments, phenylephrine (PE, 1 nM- 30 μM) caused significantly higher contractions in SERCA2 b/b than in SERCA2 a/b mice with a near-significant shift of the concentration response curve to the left ( Figures 3A,B ).
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Contractile Behavior of Mouse Aorta Depends on SERCA2 Isoform Distribution: Effects of Replacing SERCA2a by SERCA2b.
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