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Tumor-Derived Extracellular Vesicles Impair CD171-Specific CD4<sup>+</sup> CAR T Cell Efficacy.

Front Immunol · 2020 · PMC7137471 · PMID 32296437

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While relative changes in CD4 + and CD8 + CAR T cell subpopulations expressing single, double or all three inhibitory receptors were highest after co-culture with SH-SY5Y-NTRK1 and lowest after co-culture with the parental cell control, these effects did not reach statistical significance.

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