Longitudinal Maintenance of Cognitive Health in Centenarians in the 100-plus Study.

Nevertheless, we did observe a significant decline in BI scores in these 43 cognitively stable centenarians (β, −1.06; 95% CI, −1.51 to −0.62; P < .001), but this was less than the physical decline observed in the 16 centenarians who cognitively declined from MMSE scores of 26 or higher to scores of less than 26 in 2 years (β, −1.79; 95% CI, −3.04 to −0.53; P = .01), but the difference did not reach statistical significance ( P = .19).

also in 111,027 other papers