Association of each independent SNP with AO revealed nominally significant p-values (P [rs7480166] = 8.42 × 10 −6 , P [rs62171220] = 6.33 × 10 −3 , P [rs2067390] = 4.51 × 10 −5 , P [rs144891322] = 1.14 × 10 −5 , P [rs11529293] = 1.62 × 10 −5 , P [rs585809] = 2.91 × 10 −5 , P [rs72660056] = 1.66 × 10 −3 , P [rs11857349] = 8.21 × 10 −6 , P [rs8141510] = 1.33 × 10 −3 ).
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Genome-wide association study identifies genetic factors that modify age at onset in Machado-Joseph disease.
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