In the C51 tumor model, a clear trend for a marked inhibition of tumor growth in mouse FL Rnaset2 -overexpressing clones compared to control clones was observed, with several time points showing significant difference between FL Rnaset2 and control C51 E and P cells.
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Overexpression of Murine <i>Rnaset2</i> in a Colon Syngeneic Mouse Carcinoma Model Leads to Rebalance of Intra-Tumor M1/M2 Macrophage Ratio, Activation of T Cells, Delayed Tumor Growth, and Rejection.
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