Dissecting the Genetic Basis of Variation in <i>Drosophila</i> Sleep Using a Multiparental QTL Mapping Resource.

A total of 59 genes show a nominally significant ( p < 0.05) founder strain effect correlation between the local eQTL and one or more trait-specific QTL (1–10 genes per QTL group; Supplementary Table S10 ).

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Although these correlations are highly significant, the correlation coefficients are modest, with a maximum Pearson r = |0.24|, presumably due both to estimation error, and because any relationship between the expression level of a causative gene and the phenotype it controls is not direct.

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Among-trait correlations in the DSPRF1 genotype panel are generally modest, but extremely significant given the size of the dataset ( Supplementary Table S2 ).

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