Despite the limited number of sample pairs, there was a clear trend towards substantially lower DNA methylation signal obtained from post-surgery samples; the level of decrease varied greatly from about twofold to several hundred folds ( Figure 4(c,d) ).
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DNA methylation biomarkers discovered <i>in silico</i> detect cancer in liquid biopsies from non-small cell lung cancer patients.
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The sentences
The data show highly significant differences in the level of DNA methylation of the marker loci between plasma cfDNA from NSCLC patients and control subjects.