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Effect of an Enhanced Paramedic Acute Stroke Treatment Assessment on Thrombolysis Delivery During Emergency Stroke Care: A Cluster Randomized Clinical Trial.

JAMA Neurol · 2020 · PMC7154959 · PMID 32282015

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Smaller differences in door-to-needle and onset-to-needle times did not reach statistical significance, presumably reflecting influences external to the study intervention (ie, public response to symptoms and ambulance availability) and reduced statistical power.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.