Schizophrenia-associated genomic copy number variants and subcortical brain volumes in the UK Biobank.

Left hippocampus, showed a nominally significant volume reduction in 15q11.2deletion carriers compared to non-CNV carriers ( B = −0.46, SE = 0.18, p = 0.013, p FDR = 0.066), whereas carriers of any other SZ-CNVs showed no significant difference (Fig. 1 and Supplemental Tables 3 and 4 ).

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The right hippocampus and left putamen showed a trend towards significance in mediating the association ( B = −0.02, p = 0.063; B = −0.02, p = 0.060), whereas right accumbens and left pallidum were not significant.

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