Statin Drugs Plus Th1 Cytokines Potentiate Apoptosis and Ras Delocalization in Human Breast Cancer Lines and Combine with Dendritic Cell-Based Immunotherapy to Suppress Tumor Growth in a Mouse Model of HER-2^pos Disease.

IFN-γ EliSpot analysis of healthy donor Peripheral Blood Mononuclear Cells (PBMCs) stimulated with a pool of common viral peptide recall antigens ( Figure 8 A,B, left panels) or tetanus toxoid ( Figure 8 A,B, right panels) showed no more than mild simvastatin-induced diminution of spot-forming cells, which did not reach statistical significance.

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