26 In the EXAMINE study, patients with recent acute myocardial infarction treated with alogliptin also showed a trend of slight increase in admission to hospital for HF, although not statistically significant [hazard ratio (HR) 1.19, 95% CI 0.89–1.58, P = 0.22]. 27 On the contrary, the VIVIDD study, which evaluated the effect of vildagliptin on ventricular function in HFrEF diabetic patients with NYHA Fc I to III
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Prescription patterns of diabetes medications influencing clinical outcomes of heart failure patients with reduced ejection fraction.
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