As the result, the mRNA levels of IL-17 cytokines family were significantly upregulated after 10 μg/ml LPS challenge, and their expression levels generally showed a trend of first increasing, then decreasing, and finally stabilizing with the increasing of LPS concentration (Fig. 6 ).
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Transcriptomic analysis of sea cucumber (Holothuria leucospilota) coelomocytes revealed the echinoderm cytokine response during immune challenge.
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