The value of moderate dose escalation for re-irradiation of recurrent or second primary head-and-neck cancer.

2 c and d). Separating Kaplan-Meier OS curves according to treatment-related factors showed that administration of a radiation boost and completion of the planned radiotherapy resulted in improved survival rates ( p < 0.05, log-rank tests), whereby patients receiving increased re-irradiation doses of > 50 Gy showed a trend towards superior survival ( p = 0.080) (Fig. 3 a-c).

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