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Transcriptional downregulation of MHC class I and melanoma de- differentiation in resistance to PD-1 inhibition.

Nat Commun · 2020 · PMC7171183 · PMID 32312968

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HLA-A downregulation was also not related to IFN-γ gene sets and although we detected downregulation of B2M in a number of HLA-A low tumors, this did not reach statistical significance (Supplementary Fig. 4C ).

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