Significant reductions were found in the studies, which had assessed the effects of grape extract (WMD: −0.72 mg/L, 95 % CI: −1.31, -0.13; P=0.016), and a tendency towards significance was observed in the studies, which had prescribed higher amounts of grape polyphenols (>200 mg/d) (WMD: −0.67 mg/L, 95 % CI: −1.34, 0.01; P=0.053).
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Effect of grape polyphenols on selected inflammatory mediators: A systematic review and meta-analysis randomized clinical trials.
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