However, the Jonckheere Terpstra patterned rank test, which allows detection of trends among different groups, showed a significant trend towards lower CD62L − neutrophils in the blood in TiterMax® immunized mice, indicating that induction of experimental EBA leads to an activation of neutrophils within the circulation (Figure 3 ). 3.5 Immune complex‐induced activation of neutrophils is not influenced by anti‐FcRn treatment We next evaluated the effects of the FcRn on neutrophil activation in vitro.
← all excerpts
Treatment with anti-neonatal Fc receptor (FcRn) antibody ameliorates experimental epidermolysis bullosa acquisita in mice.
1
—
—