Furthermore, the reduction in carbapenem consumption was accompanied by maintenance in antibiotic-free days in the intervened ward, a finding not replicated in the control ward, where we observed a negative trend in antibiotic-free days.
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Persuasive antimicrobial stewardship intervention in the context of a KPC outbreak: a controlled interrupted time series analysis.
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In the Vascular Surgery ward a significant decreasing trend in intervention period was noticed while in the control ward the opposite occurred (Table 2 ). Antibiotic free-days In both wards a positive trend, reflecting an increasing number of antibiotic-free days, was noticed in pre-intervention period (Fig. 4 ).
Results The AMS intervention produced a level change in carbapenem consumption of − 11.14 DDDs/100 patient-days accompanied by a decreasing trend of total antibiotic consumption and stable rate of antibiotic-free days in Vascular Surgery ward.