Apatinib Combined with Local Irradiation Leads to Systemic Tumor Control via Reversal of Immunosuppressive Tumor Microenvironment in Lung Cancer.

The results showed a trend toward mildly reduced frequency of white blood cells counts in mice treated with both single modality of apatinib (200 mg/kg) and combined strategy with SABR, without showing any other myelosuppressive toxicity ( Fig. 2B ). 2.

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