The ULK1/2 and AMPK Inhibitor SBI-0206965 Blocks AICAR and Insulin-Stimulated Glucose Transport.

Despite this marked effect of SBI-0206965 on glucose transport, the effect on basal and AICAR-stimulated AMPK Thr172 phosphorylation did not reach statistical significance ( Figure 2 A,B), whereas Acetyl Coenzyme A carboxylase (ACC) Ser212 phosphorylation was partially reduced by SBI-0206965 in both EDL and soleus muscle ( Figure 2 C,D).

also in 111,027 other papers