However, this is a controversial issue, mainly because the presence of TgAb may not be useful in a significant proportion of patients due its low prevalence [ 14 ], and also because there is as yet no clear definition of the magnitude of TgAb level variation and the period of time over which it occurs that would be necessary for it to be regarded as a significant trend in their concentrations.
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Prognostic Significance of Thyroglobulin Antibodies in Differentiated Thyroid Cancer.
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Patients with positive TgAb presented a highly significant RR of persistent or recurrent disease (not quantifiable due to the absence of cases with active disease in the group of patients whose TgAb decreased significantly or disappeared). 4.