Pre-existing neutralizing antibodies prevent CD8 T cell-mediated immunopathology following respiratory syncytial virus infection.

Similar to CD25 expression, IgG and mAb43 administration resulted in an increase in CD69 expression compared with either motavizumab or D25 treatment on day 2 p.i., although the increase compared with motavizumab-treated mice did not reach statistical significance (Fig. 4c, d ).

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