Envelope stress responses defend against type six secretion system attacks independently of immunity proteins.

Deletion of the wcaJ gene, resulting in loss of colanic acid while also abolishing potentially toxic intermediates during its synthesis 29 , also showed reduced survival compared to wild-type with a nearly significant p-value of 0.0527 ( Extended Data Fig. 3c ); however this difference in severity suggests that accumulating intermediates may further sensitize the wza and wcaA mutants to TseH.

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