Virus-Like Particles Derived From a Virulent Strain of Pest des Petits Ruminants Virus Elicit a More Vigorous Immune Response in Mice and Small Ruminants Than Those From a Vaccine Strain.

In contrast, VNA titers of Tibet/30 VLP-vaccinated sheep only reached statistical significance by comparison to the PBS control group 12 weeks after primary vaccination with this significance sustained 15 weeks after primary vaccination ( Figure 4B ), whereas VNA titers for Nigeria 75/1 VLP-vaccinated sheep did not reach statistical significance by comparison to the PBS control at any point ( Figure 4B ).

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