Polymorphisms in miRNA binding sites involved in metabolic diseases in mice and humans.

After correction for multiple testing, the enrichment in gWAT and skeletal muscle was still significant (p-values: 0.006, 0.046 respectively); liver genes showed a trend for enrichment (p-value: 0.064).

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However, the analysis is based on highly significant enrichments and transcriptome data, and thus, relies on a solid statistical basis to detect reliable interactions, as already proven in a previous study 8 .

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