Prospective observational evaluation of radiation-induced late taste impairment kinetics in oropharyngeal cancer patients: Potential for improvement over time?

Clin Transl Radiat Oncol · 2020 · PMC7191583 · PMID 32373720

Europe PMC DOI

hedged sentences

0.0580

closest p · 1.2× alpha

0.0580

boldest claim

The sentences

tended towards significancep = 0.058so close (0.05 < p ≤ 0.1)

In patients with taste assessment in subsequent years, a significant reduction in taste impairment was found from the second to the third year (p = 0.001) and tended towards significance from the third to the fourth year (p = 0.058).

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a trend towards significancep = 0.058so close (0.05 < p ≤ 0.1)

While the MDASI taste item scores were comparable in the second and third year, as well as from the seventh year on, a significant difference could be found in the fifth (p = 0.044) and sixth year (p = 0.018) with lower taste alteration in the non-chemotherapy cohort and a trend towards significance in the fourth (p = 0.058) year after end of RT.

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