Acromegaly in preadolescence: A case report of a 9-year-old boy with acromegaly.

Whereas there are standardized cutoff points in the adult population, these cannot be accurately extrapolated and adapted for management in this younger population.[ 7 ] For example, the 9-year-old boy described here had a heel pad measurement of 18.5 mm, which may be quite significant for his age but fell far below the adult cutoff of 21 mm, thus making it appear clinically insignificant.[ 16 ] It is believed that serial increments in the parameters of a particular child expressed as velocity increase may be more helpful in diagnosing acromegaly in this population than simply using cut-off points.[ 7 ] In addition to clinical assessment, biochemical analysis and brain imaging contribute to making a diagnosis of acromegaly and confirming the presence of pituitary adenoma or hyperplasia.

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