Impact of cytogenetic abnormalities on outcomes of adult Philadelphia-negative acute lymphoblastic leukemia after allogeneic hematopoietic stem cell transplantation: a study by the Acute Leukemia Working Committee of the Center for International Blood and Marrow Transplant Research.

Haematologica · 2020 · PMC7193485 · PMID 31558669

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did not reach statistical significanceno p-value reported

Patients with high hyperdiploidy had an estimated 54% lower risk of relapse, whereas those with del(7q), t(8;14), t(11;19), del(11q), or a tetraploid/near triploid karyotype had a HR of at least 40% higher for relapse, which did not reach statistical significance ( Figure 3 ).

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