a clear trendP = 0.0635
Moreover, although statistical analysis failed to find significant difference, we found a clear trend of increase in both GAD2 and GFAP protein expression in the putamen of dyskinetic macaques (Mann-Whitney test, GAD2: control versus MPTP + l -DOPA, P = 0.0635; GFAP: control versus MPTP + l -DOPA, P = 0.1111; Fig. 6G ) but not in parkinsonian monkeys ( Fig. 6G ).