Which interactions matter in economic evaluations? A systematic review and simulation study.

BMC Med Res Methodol · 2020 · PMC7203889 · PMID 32380948

Europe PMC DOI

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did not reach statistical significanceno p-value reported

Only three studies (8%) observed statistically significant interactions for the primary endpoint, although nine others (23%) observed large or qualitative interactions that did not reach statistical significance or for which significance was not reported.

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