Natural Variation of Vitamin D and Neurofilament Light Chain in Relapsing-Remitting Multiple Sclerosis.

Front Neurol · 2020 · PMC7205013 · PMID 32425877

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a strong trendno p-value reported

However, in a two-year double-blinded RCT of high-dose oral vitamin D 3 supplementation (20,000 IU/week) in another cohort of 68 patients with RRMS with lower disease activity we found only a strong trend for a reduction among patients without DMTs and no overall effect of increasing serum 25(OH)D levels on serum levels of NfL ( 10 ).

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