Negligible senescence in naked mole rats may be a consequence of well-maintained splicing regulation.

Similarly, the core spliceosome element Sf3b1 did not show any alterations in brain expression levels either during developmental phases or during ageing, with the exception of a single nominally significant reduction in expression of Sf3b1 in the 13–15-year-old group (beta coefficient: − 0.275; p = 0.006; Supplementary table S6 ).

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