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Distinct iron homeostasis in C57BL/6 and Balb/c mouse strains.

Physiol Rep · 2020 · PMC7210116 · PMID 32385968

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While Balb/c enterocytes showed a trend of increased LIP compared to BL/6 (Figure 4e and f ), Balb/c colonocytes harbored 8‐fold more intracellular LIP (Figure 4g and h ). 3.4 Balb/c mice are more refractory to LPS‐induced hypoferremia of inflammation Hypoferremia of inflammation is a primitive, protective innate immune response that depletes circulating iron during infection and inflammation.

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