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Maternal high-fat diet exaggerates diet-induced insulin resistance in adult offspring by enhancing inflammasome activation through noncanonical pathway of caspase-11.

Mol Metab · 2020 · PMC7210595 · PMID 32272237

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However, unexpectedly, the protein expression level of cleaved caspase-1 after metabolic activation tended to be higher in O-HFD than that in O-ND, although this did not reach statistical significance ( Figure 6 G,H).

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