Effects of lifestyle modification in polycystic ovary syndrome compared to metformin only or metformin addition: A systematic review and meta-analysis.

Sci Rep · 2020 · PMC7210926 · PMID 32385376

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only marginally significantno p-value reported

Daily dosage and duration of metformin are not related to the magnitude of reduction in serum testosterone levels, and reduction in serum testosterone levels from metformin was classified into two categories 25 ; in non-obese women, metformin significantly reduced serum testosterone levels, whereas it resulted in only marginally significant reduction in obese women.

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