Cardiac and Muscle Injury Might Partially Contribute to Elevated Aminotransferases in COVID-19 Patients.

However, the difference in alanine aminotransferase did not reach statistical significance between patients with acute cardiac injury and without it (28.5 vs 23.0; P = .11). 4 Meanwhile, the heart may occasionally contain a high alanine aminotransferase activity, 5 so abnormal levels of alanine aminotransferase and aspartate aminotransferase might partly result from myocardial injury, especially when increases of aspartate aminotransferase are more prominent.

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