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The multicomponent medication Spascupreel attenuates stress-induced gut dysfunction in rats.

Neurogastroenterol Motil · 2020 · PMC7217055 · PMID 32059072

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showed a trendP = .07so close (0.05 < p ≤ 0.1)
SP‐11 showed a trend toward attenuating the colonic hyperpermeability induced by PRS (0.95 ± 0.05 vs 0.71 ± 0.11 nmol/cm 2 /h, respectively, P = .07; Figure 3 ). 3.3 Gut transit After stress induction, colonic mean retention time significantly decreased in comparison with non‐stressed animals treated with saline (9.85 ± 0.65 vs 3.75 ± 0.52 hours, respectively, P < .01).

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