The effect of the higher 10-mg/kg dose of ciproxifan was highly significant in WT mice, but not in Gabrd KO mice.
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Increased Sensitivity of Mice Lacking Extrasynaptic δ-Containing GABA<sub>A</sub> Receptors to Histamine Receptor 3 Antagonists.
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The sentences
REM sleep suppression after 3 mg/kg ciproxifan did not reach statistical significance in either genotype.