In contrast, viscoelasticity showed a trend to decrease in animals treated with the B20 anti-VEGF-antibody but without reaching significance (mean | G ∗ | of tumor on days 6, 8 and 10: 7.1 kPa, 7.2 kPa and 6.4 kPa; p > 0.05 for each comparison; Table 1 ; Fig. 4 a).
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Magnetic Resonance Elastography reveals effects of anti-angiogenic glioblastoma treatment on tumor stiffness and captures progression in an orthotopic mouse model.
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