Causal associations of insulin resistance with coronary artery disease and ischemic stroke: a Mendelian randomization analysis.

We considered a statistical test with an observed two-sided p value <0.05 as nominally significant evidence for a potential, but yet to be confirmed, causal association; and an observed two-sided p value <0.0083 as statistically significant evidence for a causal association. 31 All analyses were conducted with R V.3.5.1 (R Development Core Team).

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