In contrast, polygenic risk scores (PRS) aggregating effects of minor alleles of independent SNPs that were adversely or beneficially associated with disability showed highly significant associations in meta-analysis, p=3.13×10-45 and p=5.60×10-23, respectively, and were replicated in each study.
Qualitative evaluation showed a positive trend between higher protein intakes and higher femoral neck and total hip BMD.
There was an increasing trend of sarcopenia by age group, it was more prevalent in women.
When patients with heart failure and reduced ejection fraction were excluded, sarcopenia appeared to be more prognostic (OR 1.96, 95% CI 0.39–9.82) although it did not reach statistical significance.