Inflammation and Trauma-Related Psychopathology in Syrian and Iraqi Refugees.

Conversely, we observed a positive trend for greater IL-1β expression predicting higher anxiety and depression symptoms severity.

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For the multivariate tests, there was no evidence of IL-1β (F(2,17) = 0.36, p = 0.70, partial η 2 = 0.04) or IL-18 (F(2,17) = 0.92, p = 0.42, partial η 2 = 0.10) differentially correlating with symptom severity by domain; the tests failed to reach significance with reduced power.

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Our data from a unique cohort of physically healthy Syrian and Iraqi refugees (relatively young, similar trauma, timing of exposure and stress of migration, and timing of data collection within the first month of their arrival in the host country) showed a negative trend for IL-1β predicting PTSD, where lower concentrations of IL-1β were associated with greater severity of post-traumatic stress symptoms.

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