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Evaluating the Role of the Steroid and Xenobiotic Receptor (SXR/PXR) in PCB-153 Metabolism and Protection against Associated Adverse Effects during Perinatal and Chronic Exposure in Mice.

Environ Health Perspect · 2020 · PMC7228131 · PMID 32352317

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RBC membranes of SXRKO mice exposed to PCB-153 showed signs of higher MDA content, indicative of higher lipid peroxidation and oxidative damage, but this did not reach statistical significance ( Figure 4B ).

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