HIV-associated gut dysbiosis is independent of sexual practice and correlates with noncommunicable diseases.

6c ) though did not reach statistical significance, and fold enrichment/depletion patterns of ASVs that differed in abundance between PWH and seronegative controls (those comprising the DI) were associated with directionality of correlations with suPAR, such that bacteria depleted in PWH correlated inversely with suPAR levels in PWH, whereas bacteria enriched in PWH correlated positively with suPAR levels (Supplementary Fig. 6d ), suggesting a link not only with alpha diversity but also with the specific taxa that are altered in abundance in PWH.

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