Saccharin Supplementation Inhibits Bacterial Growth and Reduces Experimental Colitis in Mice.

Nutrients · 2020 · PMC7230785 · PMID 32316544

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Surprisingly, colonic icam-1 mRNA levels were significantly decreased after five days of saccharin supplementation compared to controls, while ileal icam-1 mRNA expression showed a trend towards reduction ( p ≤ 0.08) after three days of saccharin intake compared to controls ( Figure 2 f).

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