Barely Significant
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Moderate Weight Loss Modifies Leptin and Ghrelin Synthesis Rhythms but Not the Subjective Sensations of Appetite in Obesity Patients.

Nutrients · 2020 · PMC7230904 · PMID 32230732

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a slight trendno p-value reported
Only high-density lipoprotein-associated cholesterol (cHDL) showed a slight trend towards better values in the control subjects, but as mentioned, the differences did not reach statistical significance.

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