Composite contributions of cerebrospinal fluid GABAergic neurosteroids, neuropeptide Y and interleukin-6 to PTSD symptom severity in men with PTSD.

There was a borderline significant positive association between CSF IL-6 levels and PTSD severity (β = 0.423, p = 0.05), while controlling for NPY and the progesterone-derived GABAergic neurosteroid levels. 3.5 Results plotted at the individual patient level Illustrating the findings at the individual patient level, Fig. 1 depicts Z

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While not statistically significant, there also was a strong trend for higher CSF IL-6 levels in this relatively small sample of men with PTSD compared to trauma-exposed men without PTSD.

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