nearly significantP = 0.052
Myostatin levels were significantly decreased ( P = 0.010), and irisin levels showed a nearly significant reduction ( P = 0.052) in the dapagliflozin group compared with the control group, whereas FGF21 levels did not change significantly from baseline to the end of the intervention in both the dapagliflozin ( P = 0.673) and the control ( P = 0.823) groups.