Relationships of handgrip strength with the presence of cerebral microbleeds and platelet count in older Japanese adults.

Although this association was not present in participants a high platelet count, there was a positive trend in those with a low platelet count (B = 0.50, p = 0.135).

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Compared with those participants with a high platelet count, those with a low platelet count were more likely to have chronic kidney disease (CKD) and use non-vitamin K antagonist oral anticoagulants (NOACs) more frequently, had a higher serum cystatin C concentration, and had a lower low-density lipoprotein (LDL)-cholesterol concentration. In the simple linear regression analysis, although the association between handgrip strength and the presence of CMBs was not significant, there was a negative trend among the total participants (B coefficient = −3.00, p = 0.218) ( Table 2 ).

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