Adaptation of the master antioxidant response connects metabolism, lifespan and feather development pathways in birds.

We found highly significant evidence of positive selection acting on Avian GSTA2 ( p < 10 −17 ; M8 PAML, Supplementary Table 9 ) and identified with high statistical confidence (posterior probabilities >0.99) several GSTA2 sites targeted by this acceleration in evolutionary rates ( d N / d S = 3.50; Fig. 4a ).

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Across all MS-BMR groups, there is a clear trend of higher lifespan ranges in Neoaves compared to that of basal Aves (Fig. 5d ).

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